AVAILABLE INFORMATION FOR
(GLIPTAGREAT M 500 TABLET)

SALT INFORMATION
Vildagliptin 50 MG + Metformin 500 MG

VILDAGLIPTIN 50 MG
Use
Vildagliptin is an oral Anti-Hyperglycemic Agent (anti-diabetic drug). it inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.
Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus.
Common Side Effect
It include nausea, hypoglycemia, tremor, headache and dizziness.Rare cases of hepatoxicity have been reported.
Class of Drugs - Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Route of Administration - Oral
Bioavailability - 85%
Biological Half Life - 2-3 Hours

METFORMIN 500 MG
Use
Metformin is the first-line medication for the treatment of type 2 diabetes. It is also used in the treatment of polycystic ovary syndrome.
Common Side Effect
Includes gastrointestinal irritation, diarrhea, cramps, nausea, vomiting, increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs.
Precaution
It should not be used in those with significant liver disease or kidney problems.
Class of Drug - Biguanide Class
Route of Administration - Oral
Bioavailability - 50–60%
Biological Half Life - 4-8.7 Hours
Excretion - Urine 90%