AVAILABLE INFORMATION FOR
(CARDACE AM 2.5 TABLET)

SALT INFORMATION
Amlodipine 5 MG + Ramipril 2.5 MG

AMLODIPINE 5 MG
Use
It is used in the management of hypertension and coronary artery disease (chronic stable angina, vasospastic angina).It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease.
Common Side Effect
Include peripheral edema, dizziness, palpitations, flushing, fatigue, nausea, abdominal pain, somnolence, insomnia.
Precaution
Avoid if you are in shock including shock caused by heart problems, if you have severe low blood pressure (hypotension), have liver problems or if you are taking antifungal drugs (ketoconazole or itraconazole), antibiotic drugs (rifampicin, erythromycin, clarithromycin).
Class of Drug - Angioselective Calcium Channel Blocker
Route of Administration - Oral
Bioavailability - 64 to 90%
Biological Half Life - 30 to 50 Hours
Excretion - Kidney

RAMIPRIL 2.5 MG
Use
It is used to treat high blood pressure (hypertension) and congestive heart failure. By inhibiting an enzyme, ACE inhibitors relax the muscles around small arteries (arterioles). The arterioles expand and allow blood to flow through more easily. This reduces blood pressure.
Common Side Effect
Includes shakiness, dry cough, dizziness, fatigue, especially in the early stages, nausea, fainting.
Precaution
If you have diabetes, do not use ramipril together with any medication that contains aliskiren, avoid if you have kidney disease (or if you are on dialysis), liver disease, diabetes, do not use if you are pregnant.
Class of Drug - Angiotensin-Converting Enzyme (ACE) Inhibitor
Route of Administration - Oral
Bioavailability - 28%
Biological Half Life - 2-4 Hours
Excretion - Renal (60%) and Fecal (40%)