AVAILABLE INFORMATION FOR
(TELPRES AMH TABLET)

SALT INFORMATION
Telmisartan 40 MG + Amlodipine 5 MG + Hydrochlorothiazide 12.5 MG

TELMISARTAN 40 MG
Use
Used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It works by relaxing blood vessels so blood can flow more easily.
Common Side Effect
Edema (swelling of arms, legs) sinus pain, congestion, headache, dizziness, nausea and allergic reactions.
Precaution
Contraindicated with medicines like Aliskiren, Digoxin, Lithium, Non-Steroidal Anti-Inflammatory Agents including Selective Cyclooxygenase-2 Inhibitors (COX-2 Inhibitors).care should be taken in diabetic patients. Avoid alcohol consumption.
Class of Drug - Angiotensin Receptor Blockers (ARB)
Route of Administration - Oral
Bioavailability - 50% (42–100%)
Biological Half Life - 24 Hours
Excretion - Bile 97%

AMLODIPINE 5 MG
Use
It is used in the management of hypertension and coronary artery disease (chronic stable angina, vasospastic angina).It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease.
Common Side Effect
Include peripheral edema, dizziness, palpitations, flushing, fatigue, nausea, abdominal pain, somnolence, insomnia.
Precaution
Avoid if you are in shock including shock caused by heart problems, if you have severe low blood pressure (hypotension), have liver problems or if you are taking antifungal drugs (ketoconazole or itraconazole), antibiotic drugs (rifampicin, erythromycin, clarithromycin).
Class of Drug - Angioselective Calcium Channel Blocker
Route of Administration - Oral
Bioavailability - 64 to 90%
Biological Half Life - 30 to 50 Hours
Excretion - Kidney

HYDROCHLOROTHIAZIDE 12.5 MG
Use
It is a diuretic medication, used for the treatment of hypertension, congestive heart failure, symptomatic edema, diabetes insipidus, renal tubular acidosis, for the prevention of kidney stones in those who have high levels of calcium in urine and are also used in the treatment of osteoporosis.
Common Side Effect
Include headache, nausea, vomiting, photosensitivity, gout or weight gain.
Precaution
Avoid using hydrochlorothiazide, if you have liver disease, kidney disease, glaucoma, asthma, or if you are allergic to sulfa drugs or penicillin. Avoid drinking alcohol, which can increase some of the side effects of this medicine.
Class of Drug - Dihydropyridine Class of Calcium Channel Blocker (Novel Calcium Antagonist)
Route of Administration - Oral
Bioavailability - Variable (~70% on average)
Biological Half Life - 5.6–14.8 Hours
cretion - Primarily kidney (>95% as Unchanged Drug)