AVAILABLE INFORMATION FOR
(NT GRAIN TABLET)

SALT INFORMATION
Caffeine 100 MG + Ergotamine 1 MG + Paracetamol 250 MG + Prochlorperazine 2.5 MG

CAFFEINE 100 MG
Use
Caffeine is used to restore mental alertness or wakefulness during fatigue or drowsiness. Caffeine is also found in some headache and migraine medications, in certain dietary supplements used for weight loss, and in many popular energy drinks.
Common Side Effect
Insomnia (sleep problem), Nervousness and Restlessness, Stomach irritation, Nausea and Vomiting, increased Heart Rate, Long-term consumption at sufficiently high doses has been associated with chronic arterial stiffness.
Precaution
Precaution should be taken by a Pratients with Diabetes, Panic & Anxiety disorder.
Class of Drug - Central Nervous System (CNS) stimulant
Route of Administration - By Mouth, Insufflation, Enema, Rectal, Intravenous
Biological Half Life - Adults 3–7 Hours, Infants 65–130 Hours
Bioavailability - 99%
Excretion - Urine (100%)

ERGOTAMINE 1 MG
Use
Ergotamine is used medicinally for treatment of acute migraine attacks.
Common Side Effect
Spinning sensation, Dizziness, Vomiting, Nausea, Swelling & Mild itching.
Precaution
This medicine should be used only for Migraine Headaches, it is not indicated for use for other types of headaches.
Class of Drug - Alkaloids (Ergot family)
Route of Administration - Oral
Bioavailability - IV 100%, IM 47%, Oral less than 1% (Enhanced by co-administration of caffeine)
Biological Half Life - 2 Hours
Excretion - 90% Biliary

PARACETAMOL 250 MG
Use
Paracetamol is a medication used to treat pain and fever, Osteoarthritis, Low back pain, Headaches, Postoperative & Dental pain, It is typically used for mild to moderate pain.
Common Side Effect
Acute overdoses of paracetamol can cause potentially fatal liver damage, Allergic reaction, Nausea, Stomach bleeding.
Precaution
Precaution should be taken by patients with Kidney & Liver impairment. Patients with Peptic ulcer, Gastric disorders, Hypertensives should take Carefully.
Class of Drug - Mild Analgesic [Non-steroidal Anti-inflammatory Drugs]
Route of Administration - By Mouth, through the Cheek, Rectal, Intravenous (IV)
Bioavailability - 63–89%
Biological Half Life - 1-4 Hours
Excretion - Urine (85–90%)

PROCHLORPERAZINE 2.5 MG
Use
Prochlorperazine is used for the antiemetic treatment of Nausea and Vertigo. It is also used to treat Migraine headaches.
Common Side Effect
Dizziness, Drowsiness, Sleep problems, Breast swelling or discharge, a missed Menstrual period, Orthostatic hypotension (sudden lowering of blood pressure on standing).
Precaution
Do not stop taking this medicine suddenly without informing the doctor since this may cause withdrawal symptoms.
Class of Drug - Dopamine (D2) receptor antagonist (Phenothiazine class)
Route of Administration - Oral, Buccal, Rectal, IM, IV
Bioavailability - Unknown, but presumed substantial
Biological Half Life - 4–8 Hours, differs with the method of administration
Excretion - 90% Biliary, (colored) inactive metabolites in urine