Bhopal

AVAILABLE INFORMATION FOR
(VOGLOW GM 1 FORTE TABLET)

SALT INFORMATION
Glimepiride 1 MG + Metformin 1000 MG + Voglibose 0.2 MG

GLIMEPIRIDE 1 MG
Use
It is an orally available medium-to-long-acting Sulfonylurea Antidiabetic Drug. It is used to treat Type 2 Diabetes Mellitus by increasing the insulin production by the pancreas. It is used for controlling high blood sugar and also helps prevent kidney damage
Common Side Effect
Include gastrointestinal tract disturbances, allergic reactions, skin rashes, itching, rarely blood production disorders including thrombocytopenia, leukopenia, and hemolytic anemia.
Precaution
It is not used for type 1 diabetes because in type 1 diabetes the pancreas is not able to produce insulin. Avoid if you are taking Nonsteroidal anti-inflammatory drugs (salicylates), thiazides or other diuretics, anticoagulants (warfarin) and antifungals (miconazole, ketoconazole). Alcohol consumption and exposure to sunlight should be restricted because they can worsen side effects.
Class of Drug - First Third-Generation Sulfonylurea
Route of Administration - Oral
Bioavailability - 100%
Biological Half Life - 5–8 Hours
Excretion - Urine (~60%), Feces (~40%)

METFORMIN 1000 MG
Use
Metformin is the first-line medication for the treatment of type 2 diabetes. It is also used in the treatment of polycystic ovary syndrome.
Common Side Effect
Includes gastrointestinal irritation, diarrhea, cramps, nausea, vomiting, increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs.
Precaution
It should not be used in those with significant liver disease or kidney problems.
Class of Drug - Biguanide Class
Route of Administration - Oral
Bioavailability - 50–60%
Biological Half Life - 4-8.7 Hours
Excretion - Urine 90%

VOGLIBOSE 0.2 MG
Use
It is used for lowering post-prandial blood glucose levels in people with diabetes mellitus. It delays the absorption of glucose thereby reducing the risk of macrovascular complications.
Common Side Effect
Includes blurred vision, feeling of sickness, feeling of discomfort, increased intestinal gas, numbness, abdominal pain.
Precaution
It should be used with caution in patient with liver diseases and renal function impairment.
Class of Drug - Alpha Glucosidase Inhibitor
Route of Administration - Oral
Excretion - Renal 90%

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