SALT INFORMATION
Cilndidipine 10 MG + Metoprolol 25 MG

CILNIDIPINE 10 MG
Use
It is used to manage hypertension. Due to its blocking action at N-type and L type calcium channel, cilnidipine dilates both arterioles and venules, reducing the pressure in the capillary bed. Cilnidipine prevents intracellular calcium influx and results in vasodilatation.
Common Side Effect
Peripheral edema, eye pain, headache, dizziness, flushing.
Precaution
Cilnidipine is contraindicated in patients with severe aortic stenosis, cardiogenic shock,
Cilnidipine can interact with aldesleukin, quinidine, phenytoin, rifampicin, erythromycin, other anti-hypertensive drugs and anti-psychotic drugs.
Class of Drug - Dihydropyridine Class of Calcium Channel Blocker (Novel Calcium Antagonist)
Route of Administration - Oral
Bioavailability - 64 to 90%
Biological Half Life - 2.5 Hours
Excretion - Kidney

METOPROLOL 25 MG
Use
It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate, also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines.
Common Side Effect
Include dizziness, drowsiness, fatigue, diarrhea, trouble sleeping, depression, and vision problems.
Precaution
Smoking and alcohol should be avoided as it may worsen the side effect, avoid high salt or high sodium intake in meals. Avoid if you have a slow heart rate, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat), should not be used during pregnancy.
Class of Drug - Dihydropyridine Class of Calcium Channel Blocker (Novel Calcium Antagonist)
Route of Administration - Oral
Bioavailability - 64 to 90%
Biological Half Life - 2.5 Hours
Excretion - Kidney