SALT INFORMATION
Metoprolol 25 MG + Amlodipine 5 MG
METOPROLOL 25 MG
Use
It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate, also used to prevent further heart problems after myocardial infarction and to prevent headaches in those with migraines.
Common Side Effect
Include dizziness, drowsiness, fatigue, diarrhea, trouble sleeping, depression, and vision problems.
Precaution
Smoking and alcohol should be avoided as it may worsen the side effect, avoid high salt or high sodium intake in meals. Avoid if you have a slow heart rate, problems with blood circulation, or pheochromocytoma (a tumor that develops on a gland near the kidneys and may cause high blood pressure and fast heartbeat), should not be used during pregnancy.
Class of Drug - Dihydropyridine Class of Calcium Channel Blocker (Novel Calcium Antagonist)
Route of Administration - Oral
Bioavailability - 64 to 90%
Biological Half Life - 2.5 Hours
Excretion - Kidney
AMLODIPINE 5 MG
Use
It is used in the management of hypertension and coronary artery disease (chronic stable angina, vasospastic angina).It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease.
Common Side Effect
Include peripheral edema, dizziness, palpitations, flushing, fatigue, nausea, abdominal pain, somnolence, insomnia.
Precaution
Avoid if you are in shock including shock caused by heart problems, if you have severe low blood pressure (hypotension), have liver problems or if you are taking antifungal drugs (ketoconazole or itraconazole), antibiotic drugs (rifampicin, erythromycin, clarithromycin).
Class of Drug - Angioselective Calcium Channel Blocker
Route of Administration - Oral
Bioavailability - 64 to 90%
Biological Half Life - 30 to 50 Hours
Excretion - Kidney