SALT INFORMATION
Rosuvastatin 20 MG + Clopidogrel 75 MG
ROSUVASTATIN 20 MG
Use
It is used to treat Hypercholesterolemia, hypertriglyceridemia, hyperlipidemia, mixed dyslipidemia, slowing progression of atherosclerosis and primary dysbetalipoproteinemia. It regulates the amount of cholesterol and other lipids made by your body. It does this by blocking the action of a certain enzyme (called HMG-CoA reductase) which body needs to make the fats. This lowers your risk of heart and blood vessel disease.
Common Side Effect
Includes gastrointestinal irritation, diarrhea, cramps, nausea, vomiting, increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs.
Precaution
Avoid if you have liver disease, having surgery, dental surgery, if you are Pregnant or Breastfeeding, do not consume alcohol with this medication, don't take aluminum and magnesium hydroxide antacids with Rosuvastatin, take them at least 2 hours after Rosuvastatin.
Class of Drug - Statin or (HMG-CoA Reductase Inhibitor)
Route of Administration - Oral
Bioavailability - 20%
Biological Half Life - 19 Hours
Excretion - Faeces 90%
CLOPIDOGREL 75 MG
Use
Used to reduce the risk of heart disease, prevent heart attack and stroke in those at high risk including those with a history of myocardial infarction and other forms of acute coronary syndrome, stroke, and those with peripheral artery disease .It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (Dual Antiplatelet therapy).
Common Side Effect
Bleeding, Itchy skin, Bruises, Coughing up Blood or Blood clots, Vomiting, Headache, Stomache.
Precaution
Avoid taking clopidogrel with omeprazole, esomeprazole, diabetes drug epaglinide, ibuprofen, naproxen, warfarin, aspirin and antidepressants. Avoid during bleeding as clopidogrel prevents clotting.
Class of Drug - P2Y12 Inhibitors
Route of Administration - Oral
Bioavailability - >50%
Biological Half Life - 7–8 Hours
Excretion - 50% Kidney, 46% Biliary
