SALT INFORMATION
Atorvastatin 10 MG + Ezetimibe 10 MG
ATORVASTATIN 10 MG
Use
Atorvastatin are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.
Common Side Effect
Headache, Joint Pain, Joint Swelling, Muscle Pain, Back Pain Diarrhoea, Nose Bleed, Constipation, Myopathy with elevation of creatinine kinase and rhabdomyolysis are the most serious side effects.
Class of Drug - Statin
Route of Administration - Oral
Bioavailability - 12%
Biological Half Life - 14 Hours
Excretion - Bile
EZETIMIBE 10 MG
Use
Used to lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone when other cholesterol-lowering medications are not tolerated or together with statins (e.g., ezetimibe/simvastatin) when statins alone do not control cholesterol.
Common Side Effect
Mild Stomach pain, Diarrhea, Tired feeling, Dizziness, Runny or Stuffy nose, Cold symptoms, Joint pain, Back pain.
Precaution
The two contraindications to taking Ezetimibe are a previous allergic reaction including rash, angioedema, and anaphylaxis, and severe liver disease, especially when taken with a statin. Ezetimibe may have significant medication interactions with cyclosporine and with fibrates other than fenofibrate. Avoid eating foods that are high in fat or cholesterol.
Class of Drug - Lipid-Lowering Agents, 2-Azetidinones
Route of Administration - Oral
Bioavailability - 35–65%
Biological Half Life - 19–30 Hours
Excretion - Renal 11%, Faecal 78%