SALT INFORMATION
Rosuvastatin 10 MG + Ezetimibe 10 MG
ROSUVASTATIN 10 MG
Use
It is used to treat Hypercholesterolemia, hypertriglyceridemia, hyperlipidemia, mixed dyslipidemia, slowing progression of atherosclerosis and primary dysbetalipoproteinemia. It regulates the amount of cholesterol and other lipids made by your body. It does this by blocking the action of a certain enzyme (called HMG-CoA reductase) which body needs to make the fats. This lowers your risk of heart and blood vessel disease.
Common Side Effect
Includes gastrointestinal irritation, diarrhea, cramps, nausea, vomiting, increased flatulence; metformin is more commonly associated with gastrointestinal side effects than most other antidiabetic drugs.
Precaution
Avoid if you have liver disease, having surgery, dental surgery, if you are Pregnant or Breastfeeding, do not consume alcohol with this medication, don't take aluminum and magnesium hydroxide antacids with Rosuvastatin, take them at least 2 hours after Rosuvastatin.
Class of Drug - Statin or (HMG-CoA Reductase Inhibitor)
Route of Administration - Oral
Bioavailability - 20%
Biological Half Life - 19 Hours
Excretion - Faeces 90%
EZETIMIBE 10 MG
Use
Used to lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone when other cholesterol-lowering medications are not tolerated or together with statins (e.g., ezetimibe/simvastatin) when statins alone do not control cholesterol.
Common Side Effect
Mild Stomach pain, Diarrhea, Tired feeling, Dizziness, Runny or Stuffy nose, Cold symptoms, Joint pain, Back pain.
Precaution
The two contraindications to taking Ezetimibe are a previous allergic reaction including rash, angioedema, and anaphylaxis, and severe liver disease, especially when taken with a statin. Ezetimibe may have significant medication interactions with cyclosporine and with fibrates other than fenofibrate. Avoid eating foods that are high in fat or cholesterol.
Class of Drug - Lipid-Lowering Agents, 2-Azetidinones
Route of Administration - Oral
Bioavailability - 35–65%
Biological Half Life - 19–30 Hours
Excretion - Renal 11%, Faecal 78%
